Tim Inglis

		Office:	War Memorial Gym - Room 33
		Phone:	604-822-1626
		Fax:	604-822-6842
		Lab:	Human Neurophysiology Lab oratory
		Lab Ph:	6604-822-4206
		EMail:	tim.inglis@ubc.ca
Professor

Background

University of Waterloo, Waterloo B.Sc. 1984; University of Western Ontario, London B.Sc.P.T. 1992; University of Waterloo, Waterloo M.Sc. 1986; Queens University, Kingston Ph. D. 1991

Specialization

Exercise Science – Neurophysiology, Biomechanics, Stance and Balance Control, Human Microneurography, Physical therapy and Rehabilitation, Vestibular System

Courses Taught

HKIN 290 (3) - Functional Anatomy and Applied Physiology I

Structure and function of the neuromuscular and skeletal systems of the human body. Special emphasis on movement analysis and the physiological effects of exercise. Prerequisite: HKIN 163. [2-2]

HKIN 389 (3) - Neuromuscular Integration of Human Movement

The Neurophysilogical and functional neuroanatomical processes involved in the sensory and motor control of movement, posture and balance in the human.  peripheral and central sensorimotor structures, and neurological diseases that effect human movement and balance control will be discussed.  Pre-requisite: HKIN 291

HKIN 500 - Neurophysiology of Human Movement

An examination of the neurophysiological and functional neuroanatomical processes involved in the sensory and motor control of movement, posture and balance.  Clinical examples of neurological diseases that effect human movement control may also be incorporated.  Emphasis is placed n a critical analysis of the current literature.

Research

The task of maintaining upright stance in the human involves a complex control system that can use and integrate the bounty of sensory information that surrounds us. The long term goal of my basic research program is to better understand the fundamental role played by sensory information in the control of standing balance and movement in humans. To investigate this focus, I have developed two research laboratories in the School of Human Kinetics at the University of British Columbia. In the Human Neurophysiology laboratory, I use a special research technique, termed microneurography, to record the lower-limb somatosensory neural activity of conscious human subjects. Currently, there are no other microneurography laboratories in Canada, and approximately only 8-10 single-unit microneurography laboratories worldwide that use this technique to investigate sensorimotor research issues. Research in the Human Microneurography laboratory at UBC is funded by equipment and operational grants provided by NSERC, and by three collaborative NIH (National Institute of Health, U.S.) funded grants with a laboratory in the United States (Dr. Paul Cordo, OHSU, Portland, Oregon).

In the Human Balance Control laboratory, I use conventional biomechanical techniques to analyze how standing balance and locomotion can be affected by manipulating the sensory inputs. In particular, I use another novel research technique, termed galvanic vestibular stimulation, to artificially alter the human vestibular system (inner ear balancing system). Work in this lab has been established through startup funding provided by UBC, and collaborative efforts with Boston University (Dr. Jim Collins, NIH) and Laval University (Brad McFadyen, NSERC). Research investigating balance and postural control post-Stroke are also being carried out at G.F. Strong in the Laboratory of Dr. Janice Eng (School of Rehab Sciences) that are funded through a CIHR grant awarded to Dr. Eng. Other work about to get underway involves the investigation of unexpected slips and falls with Dr. Gunter Siegmund, and Dr. David Sanderson (Human Kinetics) (WCB).

Finally, collaborative work with Dr. Bill Sheel (Human Kinetics) and Stacy Elliot (Medicine) on the sexual consequences of spinal cord injury are being started Jan. 2003, and are linked through ICORD : http://www.icord.org

Current Projects:

1. Microneurographic recordings from somatosensory receptors in standing human subjects {NSERC}.

2. A system for recording from peripheral nerves in conscious human subjects {NSERC}.

3. Stochastic Resonance in human muscle spindles (with P. Cordo, RSDOW, NSI, Oregon, U.S.A.) {National Institute of Health, R01 operations grant, U.S.A.}

4. An artificial Vestibular System (with J.J. Collins, Boston University) {National Institute of Health, R23 operations grant, U.S.A.}

5. Cortical Magnetic Stimulation (with I. Franks, D. Sanderson, D. Goodman) {NSERC)

6. Vestibular contributions to the control of human dynamic equilibrium (with B. Macfadyen, University of Laval). (NSERC)

7. Reflex contributions to muscle of lower limb cutaneous and muscle afferents. (with A.G. Cresswell, Karolinska Institute, Sweden).

Publications

Scholarly Articles  (students in italics)

1. Anthony N. Carlsen, Micheal A. Hunt, J.Timothy Inglis, David J. Sanderson and Romeo Chua. Altered triggering of a prepared movement by a startling stimulus. J. Neurophysiology in press.

2. Craig D. Tokuno, David J.Sanderson, J. Timothy Inglis, and Romeo Chua. Postural and movement adaptations by individuals with a unilateral below-knee amputation during gait initiation. Gait & Posture, in press.

3. Gunter P. Siegmund , David J. Sanderson, Barry S. Myers, J. Timothy Inglis. Rapid adaptation to multiple seated perturbations: Implications for the study of whiplash injury using human subjects. J. Biomechanics, in press.

4. Anthony P. Scinicarello, J. Timothy Inglis and J. J. Collins. The effects of monopolar, stochastic vestibular stimulation on human postural sway. J. Vestibular Res, in press.

5. G.P. Siegmund , D.J. Sanderson, B. S. Myers, and J. T. Inglis. Awareness affects the neck muscle and kinematic responses of human subjects exposed to a single whiplash-like perturbation. Spine, in press.

6. Paul M. Kennedy and J. Timothy Inglis. Interaction effects of galvanic vestibular stimulation and head position on the soleus H reflex in humans. Clinical Neurophysiology, (2002) 113(11):1709-1714.

7. Leah R. Bent, Bradford J. McFadyen and J. Timothy Inglis. The role of vestibular information on step initiation: Visual and Vestibular interactions. Exp. Brain Res. (2002) 146: 490-500.

8.J. T. Inglis, P. M. Kennedy, C. Wells, R. Chua. The role of cutaneous receptors in the foot. Adv. Exp. Med. Biol, (2002) 508:111-117.

9. G.P. Siegmund , D.J. Sanderson, J. T. Inglis. The influence of perturbation amplitude awareness on the reflex neck muscle response of seated subjects. Exp. Brain Res, (2002)144:314-321.

10. Paul J. Cordo, Carmen Flores-Vieira, Sabine M.P. Verschueren, J. Timothy Inglis and Victor Gurfinkel. Static position sensitivity of human muscle spindles: single afferent and population respresentations. J. Neurophysiology, (2002) 87: 1186-1195.

11. Leah R. Bent, J. Timothy Inglis and Bradford J. McFadyen. The effects of galvanic vestibular stimulation on step initiation. Exp. Brain Res., (2002) 143: 100-105.

12. P.M. Kennedy and J.Timothy Inglis. Distribution and behaviour of glabrous cutaneous receptors in the human foot sole. J. Physiology, (2002) 538.3:995-1002.

13. P.M. Kennedy and J.Timothy Inglis. Interaction of Galvanic vestibular stimulation with tonic neck reflexes. Clinical Neurophysiology, (2001) 112 (11): 2159-2163.

14. Trevor B. Birmingham, John F. Kramer, Sandy Kirkley, J. Timothy Inglis, Sandi J. Spaulding and Tony Vandervoort. Association among neuromuscular and anatomical measures for patients with knee osteoarthritis. Arch Phys Med Rehab, (2001) 82: 1115-1118.

15. G.P. Siegmund, J. Timothy Inglis & D.J.Sanderson. Startle response of neck muscles sculpted by readiness to perform ballistic head movements. J. Physiol. (2001) 535.1:289-300

16. Trevor B. Birmingham, John F. Kramer, Sandy Kirkley, J. Timothy Inglis, Sandi J. Spaulding and Tony Vandervoort. Knee bracing following ACL Reconstruction: Effects on Postural control and proprioception. Med Sci Sport Ex, (2001) 33 (8): 1253-1258.

17. Anthony P. Scinicarello, Kenneth Eaton, J. Timothy Inglis and J. J. Collins. Enhancing human balance control with galvanic vestibular stimulation. Biological Cybernetics, (2001) 84: 475-480.

18. Trevor B. Birmingham, John F. Kramer, Sandy Kirkley, J. Timothy Inglis, Sandi J. Spaulding and Tony Vandervoort. Knee bracing for medial compartment Osteoarthritis: Effects on Proprioception and postural stability. Rheumatology, (2001) 40(3):285-289.

19. Tim McGarry, J. Timothy Inglis and Ian M. Franks. Against a final ballistic process in the control of voluntary movement: Evidence using the Hoffmann Reflex. Motor Control (2000) 4:469-485.

20. Trevor Birmingham, J. Timothy Inglis, John Kramer, Tony Vandervoort, Shahira Bhimini, and Jens Tans. Effect of a Neoprene Sleeve on Knee Joint Kinesthesis: Comparison of Active, Passive and Axially loaded Joint Angle Replication Tests. Med Sci Sports Ex, (2000) 32 (2):304-308.

21. Leah R. Bent, Bradford J. McFadyen, Veronique French Merkley, Paul M. Kennedy and J. Timothy Inglis. Magnitude effects of Galvanic vestibular stimulation on the trajectory of human gait. Neuroscience Letters, (2000) 279(3):157-160.

22. LR Wilson, SC Gandevia, JT Inglis, J-M Gracies and D Burke. Muscle spindle activity in the affected upper limb after a unilateral stroke. Brain, (1999) 122 (11):2079-2088.

23. AE Pavlik, JT Inglis, M Lauk, L Oddsson and JJ Collins. The effects of stochastic galvanic vestibular stimulation on human postural sway. Exp. Brain Res, (1999) 124:273-280.

24. J. Timothy Inglis, James B. Leeper, Linda R. Wilson, Simon C. Gandevia and David Burke. The development of conduction block in single human axons following a focal nerve injury. J. Physiol, (1998) 513.1:127-133.

25. TB Birmingham, JF Kramer, JT Inglis, CA Mooney, LJ Murray, P Fowler and A Kirkley. Effect of a neoprene sleeve on knee joint proprioception during open and closed kinetic chain tests. Am J of Sports Med, (1998) Vol. 26 (4), 562-566.

26. Renate Van Leeuwen and J. Timothy Inglis. Mental practice and imagery: A potential role in stroke rehabilitation. Physical Therapy Reviews, (1998) Vol 3(1): 47-52.

27. Andrea Cleaves and J. Timothy Inglis. The effects of Vestibular stimulation on Hemineglect: Implications for Rehabilitation.Physical Therapy Reviews, (1997) Vol. 2(4): 185-195.

28. Simon C. Gandevia, Linda R. Wilson, J. Timothy Inglis and David Burke. Mental rehearsal of motor tasks recruits alpha-motorneurones but fails to recruit human fusimotor neurones selectively. J. Physiol., (1997) 505.1:259-266.

29. J. Timothy Inglis, Sabine Meunier, James D. Leeper, David Burke and Simon C. Gandevia. Weakshort-latency spinal projections to the long flexor of the human thumb. Exp. Brain Res., (1997) 115:165-168

30 .Paul J. Cordo, J. Timothy Inglis, Sabine Verschueren, James J. Collins, Daniel M. Merfeld, Scott Buckley, Stuart Rosenblum and Frank Moss. Noise in human muscle spindles. Nature, (1996) 769-770.